Stephen Fremes completed medical school at the University of Toronto in 1979 and then entered surgical residency in 1979 at the University of Toronto. Dr. Fremes completed general surgery residency in 1986 and cardiovascular and thoracic surgery residency in 1988. Dr. Fremes was a Research Fellow of the Heart and Stroke Foundation of Canada from 1982 to 1984 during residency (MSc awarded 1984) and from 1988 to 1989 following residency, under the supervision of Dr. Richard Weisel. Dr. Fremes has been a staff surgeon at Sunnybrook Health Sciences Centre since 1989 and a Professor of Surgery at the University of Toronto since 2001. His primary research interest has focused on improving patient outcomes following coronary surgery. Methodologies include clinical trials, large observational studies, systematic reviews and meta-analysis, guideline development and modelling.